assembly factor for spindle microtubules

Summary
Gene Symbol
  • ASPM
Organism
Homo sapiens (human)
NCBI Gene
259266
PubChem
259266
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Calmodulin-binding
  • Coiled coil
  • Cytoplasm
  • Cytoskeleton
  • Disease variant
  • Intellectual disability
  • Mitosis
  • Nucleus
  • Phosphoprotein
  • Primary microcephaly
  • Reference proteome
  • Repeat
Proteins
Displaying all 2 entries
UniProt Protein Name
B3KWI2
Q8IZT6
  • Abnormal spindle protein homolog
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Abnormal spindle-like microcephaly-associated protein like protein
Functional Category
  • G: Carbohydrate transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
calmodulin binding
establishment of meiotic spindle localization
Displaying 1 entry
InterPro
IQ motif, EF-hand binding site
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0070280 primary autosomal recessive microcephaly 5
DOID:0070296 primary autosomal recessive microcephaly

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025