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nectin cell adhesion molecule 3

Summary

Gene Symbol

NECTIN3

Organism

Homo sapiens (human)

External Links

NCBI Gene

25945

PubChem

25945

Alliance of Genome Resources

HGNC:17664

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NQS3	CDw113 Nectin cell adhesion molecule 3 Poliovirus receptor-related protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
lens morphogenesis in camera-type eye	IEA
homophilic cell adhesion via plasma membrane adhesion molecules	ISS
homophilic cell adhesion via plasma membrane adhesion molecules	IBA
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISS
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to cell junction

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

reproductive process [inference]

fertilization

developmental process [inference]

anatomical structure morphogenesis [inference]

lens morphogenesis in camera-type eye

embryonic morphogenesis [inference]

cochlea morphogenesis

retina morphogenesis in camera-type eye

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to cell junction

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane

protein localization to cell junction

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of postsynapse organization [inference]

regulation of postsynapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	TAS
cell-cell junction	ISS
adherens junction	IBA
axon	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

anchoring junction [inference]

cell-cell junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19011627 21982860 22902367 23758976 25416956 31515488 32296183 32814053 33961781
identical protein binding	IPI	22902367
protein homodimerization activity	ISS
cell adhesion molecule binding	IPI	12438620
cell adhesion mediator activity	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding

cell adhesion mediator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fasciclin-3

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 4** entries
InterPro
CD80-like, immunoglobulin C2-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **21 - 29** of 29 in total

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Species	Gene ID	Orthologous MAtrix
Rhinopithecus roxellana	104660645	RHIRO05093
Macaca nemestrina	105470416	MACNE20081
Mandrillus leucophaeus	105534552	MANLE38725
Cercocebus atys	105596250	CERAT34052
Aotus nancymaae	105723071	AOTNA29339
Dipodomys ordii	105994877	DIPOR13846
Rhinopithecus bieti	108535910	RHIBE16940
Vombatus ursinus	114047236	VOMUR11042
Saimiri boliviensis boliviensis	120360524	SAIBB25292