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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
coagulation factor VII
Summary
- Gene Symbol
-
- F7
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydroxylation
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8K3U6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to Thyroid stimulating hormone | ||
| proteolysis | ||
| response to organic cyclic compound | ||
| positive regulation of TOR signaling | ||
| response to cholesterol |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type peptidase complex | ||
| vesicle | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| endopeptidase activity | ||
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- uncharacterized protein
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080941 | acquired angioedema | |
| DOID:10763 | hypertension | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:1459 | hypothyroidism | |
| DOID:14735 | hereditary angioedema | |
| DOID:1588 | thrombocytopenia | |
| DOID:1612 | breast cancer | |
| DOID:2215 | factor VII deficiency | |
| DOID:2235 | prothrombin deficiency | |
| DOID:2349 | arteriosclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2155 | HGNC:3544 | HUMAN17719 | ||
| 14068 | 10090_1:002b44 | MGI:109325 | MOUSE57886 | |
| 114423 | ZFIN:ZDB-GENE-010814-1 | |||
| 282671 | ZFIN:ZDB-GENE-021206-10 | |||
| 607661 | CANLF08867 | |||
| 617960 | BOVIN04159 | |||
| 733661 | PIGXX01551 | |||
| 780280 | Xenbase:XB-GENE-5787186 | |||
| 100022420 | MONDO31773 | |||
| 100038778 | ZFIN:ZDB-GENE-070424-102 |
