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listerin E3 ubiquitin protein ligase 1

Summary

Gene Symbol

LTN1

Organism

Homo sapiens (human)

External Links

NCBI Gene

26046

PubChem

26046

Alliance of Genome Resources

HGNC:13082

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Reference proteome
Repeat
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
O94822	RING finger protein 160 RING-type E3 ubiquitin transferase listerin Zinc finger protein 294

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein autoubiquitination	IEA
rescue of stalled ribosome	IDA	25578875
rescue of stalled ribosome	IBA
ribosome-associated ubiquitin-dependent protein catabolic process	IDA	25578875
ribosome-associated ubiquitin-dependent protein catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein autoubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein autoubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein autoubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein autoubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein autoubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

ribosome-associated ubiquitin-dependent protein catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle disassembly [inference]

ribosome disassembly [inference]

rescue of stalled ribosome

cellular component disassembly [inference]

organelle disassembly [inference]

ribosome disassembly [inference]

rescue of stalled ribosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytosol	IDA	25578875 28757607
cytosol	IBA
cytosolic ribosome	IDA	25578875
RQC complex	IDA	25578875
RQC complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

RQC complex

cellular anatomical entity [inference]

cytosol

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21903422
zinc ion binding	IEA
ribosomal large subunit binding	IBA
ubiquitin protein ligase activity	IDA	25578875
ubiquitin protein ligase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding [inference]

ribosomal large subunit binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

e3 ubiquitin-protein ligase listerin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
metal ion binding
proteasome-mediated ubiquitin-dependent protein catabolic process
protein ubiquitination
rescue of stalled ribosome
ribosomal large subunit binding
ribosome-associated ubiquitin-dependent protein catabolic process
transferase activity

Displaying **all 3** entries
InterPro
E3 ubiquitin-protein ligase listerin
Zinc finger, RING-type
Zinc finger, RING/FYVE/PHD-type

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	26046	Xenbase:XB-GENE-1217544
Mus musculus	78913		MOUSE18741
Rattus norvegicus	288308		RATNO04833
Pan troglodytes	458494		PANTR25487
Bos taurus	519526		BOVIN14247
Macaca mulatta	714068		MACMU32218
Danio rerio	100000122		DANRE00889
Monodelphis domestica	100021202		MONDO22244
Equus caballus	100065649		HORSE25015
Taeniopygia guttata	100221893		TAEGU09756