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NADH dehydrogenase subunit 4

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

26201

PubChem

26201

Alliance of Genome Resources

RGD:620559

Annotation

Keyword

Mitochondrion
Mitochondrion inner membrane
NAD
Reference proteome
Respiratory chain
Translocase
Transmembrane helix
Ubiquinone

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8HIC6
P05508	NADH dehydrogenase subunit 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
response to hypoxia	IEP	16257962
in utero embryonic development	IEP	17307910
mitochondrial electron transport, NADH to ubiquinone	ISS
mitochondrial electron transport, NADH to ubiquinone	ISO
aerobic respiration	IBA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cerebellum development

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to chemical [inference]

response to organic substance [inference]

response to alcohol [inference]

response to ethanol

response to nicotine

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport [inference]

energy coupled proton transmembrane transport, against electrochemical gradient [inference]

electron transport coupled proton transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrion	ISO	34800366
mitochondrial inner membrane	ISS
mitochondrial inner membrane	ISO
respiratory chain complex I	ISO
respiratory chain complex I	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

NADH dehydrogenase complex [inference]

respiratory chain complex I

respiratory chain complex [inference]

respiratory chain complex I

transmembrane transporter complex [inference]

respiratory chain complex I

catalytic complex [inference]

oxidoreductase complex [inference]

NADH dehydrogenase complex [inference]

respiratory chain complex I

transporter complex [inference]

transmembrane transporter complex [inference]

respiratory chain complex I

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
NADH dehydrogenase activity	IBA
NADH dehydrogenase (ubiquinone) activity	ISS
NADH dehydrogenase (ubiquinone) activity	ISO
ubiquinone binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity [inference]

NADH dehydrogenase (ubiquinone) activity

oxidoreductase activity, acting on NAD(P)H [inference]

NADH dehydrogenase activity

NADH dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (ubiquinone) activity

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [inference]

NAD(P)H dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (ubiquinone) activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

oxidoreduction-driven active transmembrane transporter activity [inference]

NADH dehydrogenase (ubiquinone) activity

binding [inference]

quinone binding [inference]

ubiquinone binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

olfactory receptor

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
detection of chemical stimulus involved in sensory perception of smell
olfactory receptor activity
sensory perception of smell

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Olfactory receptor

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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