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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
TIAM Rac1 associated GEF 2
Summary
- Gene Symbol
-
- TIAM2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell projection
- Coiled coil
- Cytoplasm
- Guanine-nucleotide releasing factor
- Myristate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of small GTPase mediated signal transduction | ||
| positive regulation of axonogenesis | ||
| activation of GTPase activity | ||
| small GTPase mediated signal transduction |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| perikaryon | ||
| filopodium | ||
| lamellipodium | ||
| growth cone |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activator activity | ||
| guanyl-nucleotide exchange factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein still life, isoform SIF type 1
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| positive regulation of axonogenesis |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| Dbl homology (DH) domain superfamily |
| Dbl homology (DH) domain |
| PH-like domain superfamily |
| Tiam1/Tiam2/Protein still life |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070354 | cataract 48 | |
| DOID:0070444 | neurodevelopmental disorder with language delay and seizures |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 24001 | MGI:1344338 | MOUSE20663 | ||
| 43892 | FB:FBgn0085447 | |||
| 259373 | WB:WBGene00015704 | |||
| 472168 | 9598_0:001b8c | PANTR39361 | ||
| 701688 | MACMU35375 | |||
| 100032275 | MONDO11798 | |||
| 100061852 | HORSE29962 | |||
| 100079759 | ORNAN15368 | |||
| 100139161 | BOVIN36021 | |||
| 100155014 | PIGXX13187 |
