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MIRAGE
GATA binding protein 4
Summary
- Gene Symbol
-
- GATA4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Atrial septal defect
- Cardiomyopathy
- DNA-binding
- Disease variant
- Methylation
- Nucleus
- Proteomics identification
- Reference proteome
- Repeat
- Transcription regulation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | ||
| negative regulation of apoptotic signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear body | ||
| RNA polymerase II transcription regulator complex |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- GATA transcription factor
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell fate commitment |
| metal ion binding |
| sequence-specific DNA binding |
| zinc ion binding |
| InterPro |
|---|
| GATA-type transcription activator, N-terminal |
| Transcription factor GATA |
| Zinc finger, GATA-type |
| Zinc finger, NHR/GATA-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050651 | atrioventricular septal defect | |
| DOID:0110107 | atrial heart septal defect 2 | |
| DOID:1657 | ventricular septal defect | |
| DOID:1682 | congenital heart disease | |
| DOID:1882 | atrial heart septal defect | |
| DOID:6419 | tetralogy of Fallot |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105491184 | MACNE36003 | ||
| 105579385 | CERAT26924 | ||
| 105720709 | AOTNA28264 | ||
| 105811642 | PROCO19807 | ||
| 105864817 | MICMU08727 | ||
| 107557004 | SINGR62029 | ||
| 107564601 | SINGR73837 | ||
| 108273912 | ICTPU25739 | ||
| 108536704 | RHIBE22965 | ||
| 109111451 | CYPCA104874 |
