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F-box protein 5

Summary

Gene Symbol

FBXO5

Organism

Homo sapiens (human)

External Links

NCBI Gene

26271

PubChem

26271

Alliance of Genome Resources

HGNC:13584

Annotation

Keyword

3D-structure
Alternative splicing
Cytoskeleton
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UKT4	Early mitotic inhibitor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
oocyte maturation	IEA
regulation of DNA replication	IMP	17234884 17485488
DNA damage response	IMP	17875940
cellular response to DNA damage stimulus	IMP	17875940
spindle assembly involved in female meiosis I	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

microtubule polymerization or depolymerization [inference]

microtubule polymerization

cell cycle process [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

cell division

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

microtubule polymerization or depolymerization [inference]

microtubule polymerization

vesicle organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

microtubule polymerization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

microtubule polymerization

supramolecular fiber organization [inference]

microtubule polymerization

reproductive process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

developmental process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

oocyte maturation

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of mesenchymal stem cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

positive regulation of biomineral tissue development

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of nuclear division [inference]

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of cell cycle [inference]

regulation of mitotic cell cycle

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of mesenchymal stem cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

positive regulation of biomineral tissue development

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of transferase activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of ubiquitin-protein transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of ubiquitin protein ligase activity [inference]

negative regulation of ubiquitin protein ligase activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	11988738
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	IDA	11988738

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

meiotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

spindle

meiotic spindle

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GO Term	Evidence Code	PMID
protein binding	IPI	11988738 12791267 16439210 16921029 17380122 17719540 18662541 23708001 26083744 27705803 32296183 33961781
zinc ion binding	IEA
anaphase-promoting complex binding	IDA	16921029 26083744
protein kinase binding	IPI	15148369
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

anaphase-promoting complex binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

ubiquitin-protein transferase regulator activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

molecular function inhibitor activity

enzyme inhibitor activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

F-box protein 5

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
cell cycle
cell division
metal ion binding
negative regulation of cell cycle process
negative regulation of meiotic nuclear division
protein ubiquitination
regulation of mitotic nuclear division

Displaying **all 3** entries
InterPro
F-box domain
F-box only protein 5/43
Zinc finger ZBR-type domain

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	26271	Xenbase:XB-GENE-953946
Mus musculus	67141	Xenbase:XB-GENE-953946	MOUSE01487
Drosophila melanogaster	286151	FB:FBgn0017551
Rattus norvegicus	292263		RATNO16096
Pan troglodytes	463083		PANTR39336
Bos taurus	515080		BOVIN36004
Canis lupus familiaris	612020		CANLF00221
Macaca mulatta	703219		MACMU35188
Monodelphis domestica	100032184		MONDO11620
Equus caballus	100062649		HORSE29980

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements