glucosylceramidase beta 1
| UniProt | Protein Name |
|---|---|
| A0A068F658 |
|
| P04062 |
|
| B7Z6S9 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitophagy | ||
| sphingolipid metabolic process |
|
|
| glucosylceramide catabolic process | ||
| glucosylceramide catabolic process | ||
| glucosylceramide catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space |
|
|
| lysosome | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| lysosomal membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| galactosylceramidase activity | ||
| glucosylceramidase activity | ||
| glucosylceramidase activity | ||
| glucosylceramidase activity | ||
| signaling receptor binding |
| Gene Ontology |
|---|
| glucosylceramidase activity |
| sphingolipid metabolic process |
| InterPro |
|---|
| Glycoside hydrolase family 30 |
| Glycoside hydrolase superfamily |
| Glycosyl hydrolase family 30, TIM-barrel domain |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060892 | late onset Parkinson's disease | |
| DOID:0080855 | Parkinsonism | |
| DOID:0110957 | Gaucher's disease type I | |
| DOID:0110958 | Gaucher's disease type II | |
| DOID:0110959 | Gaucher's disease type III | |
| DOID:0110960 | Gaucher's disease perinatal lethal | |
| DOID:0112250 | Gaucher's disease type IIIC | |
| DOID:12217 | Lewy body dementia | |
| DOID:14330 | Parkinson's disease | |
| DOID:1926 | Gaucher's disease |
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000012 | Urinary urgency |
| HP:0000027 | Azoospermia |
| HP:0000093 | Proteinuria |
| HP:0000160 | Narrow mouth |
| HP:0000194 | Open mouth |
| HP:0000211 | Trismus |
| HP:0000218 | High palate |
| HP:0000225 | Gingival bleeding |
| Disease ID | Disease Name |
|---|---|
| ORPHA:77259 |
|
| OMIM:608013 |
|
| OMIM:231000 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101967685 | ICTTR01383 | ||
| 102029796 | CHILA23327 | ||
| 102121809 | MACFA21020 | ||
| 102189810 | CAPHI22680 | ||
| 102294992 | HAPBU19806 | ||
| 102348099 | LATCH04160 | ||
| 102425580 | MYOLU10827 | ||
| 102793518 | NEOBR25164 | ||
| 103251502 | CARSF29375 | ||
| 103388255 | CYNSE06054 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025