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Submissions

solute carrier family 27 (fatty acid transporter), member 2

Summary

Gene Symbol

Slc27a2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

26458

PubChem

26458

Alliance of Genome Resources

MGI:1347099

Annotation

Keyword

ATP-binding
Acetylation
Cell membrane
Fatty acid metabolism
Ligase
Lipid metabolism
Lipid transport
Microsome
Nucleotide-binding
Peroxisome
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O35488	Arachidonate--CoA ligase Fatty acid transport protein 2 Fatty-acid-coenzyme A ligase, very long-chain 1 Long-chain-fatty-acid--CoA ligase Phytanate--CoA ligase Solute carrier family 27 member 2 THCA-CoA ligase Very long-chain acyl-CoA synthetase Very long-chain-fatty-acid-CoA ligase
Q3TN99

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
very long-chain fatty acid metabolic process	IDA	12048192
fatty acid alpha-oxidation	ISO
fatty acid alpha-oxidation	IEA
long-chain fatty acid metabolic process	ISO
long-chain fatty acid metabolic process	TAS	15464426

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

bile acid metabolic process

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process

bile acid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

bile acid metabolic process

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

bile acid metabolic process

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process

bile acid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound metabolic process [inference]

bile acid metabolic process

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

bile acid metabolic process

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

methyl-branched fatty acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport [inference]

fatty acid transport

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell

lipid import into cell [inference]

long-chain fatty acid import into cell

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell

import into cell [inference]

long-chain fatty acid import into cell

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
mitochondrion	HDA	14651853
peroxisome	ISO
peroxisome	TAS	15464426
peroxisome	IDA	12048192 20530735
peroxisome	IMP	12719378

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
long-chain fatty acid-CoA ligase activity	ISO
long-chain fatty acid-CoA ligase activity	TAS	15464426
long-chain fatty acid-CoA ligase activity	IDA	12048192
long-chain fatty acid-CoA ligase activity	IMP	20530735
long-chain fatty acid-CoA ligase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-sulfur bonds [inference]

CoA-ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

acid-thiol ligase activity [inference]

fatty acid ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

very long-chain fatty acid-CoA ligase activity

transporter activity [inference]

lipid transporter activity [inference]

long-chain fatty acid transporter activity

oleate transmembrane transporter activity

fatty acid transmembrane transporter activity

oleate transmembrane transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

fatty acid transmembrane transporter activity

oleate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

fatty acid transmembrane transporter activity

oleate transmembrane transporter activity

binding [inference]

protein binding [inference]

enzyme binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

fatty acid ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

very long-chain fatty acid-CoA ligase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

long-chain fatty acid transport

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
long-chain fatty acid import into cell
very long-chain fatty acid-CoA ligase activity

Displaying **all 4** entries
InterPro
AMP-binding enzyme, C-terminal domain superfamily
AMP-binding, conserved site
AMP-dependent synthetase/ligase domain
ANL, N-terminal domain

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10998	Xenbase:XB-GENE-1007665
Homo sapiens	11001	Xenbase:XB-GENE-6459618	HUMAN23043
Xenopus tropicalis	26458	Xenbase:XB-GENE-1007665
Xenopus tropicalis	26459	Xenbase:XB-GENE-1007665
Rattus norvegicus	65192		RATNO27860
Pan troglodytes	453423		PANTR10297
Canis lupus familiaris	478298		CANLF12505
Sus scrofa	494011		PIGXX14349
Bos taurus	535727		BOVIN01366
Macaca mulatta	715237		MACMU42649

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements