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glial fibrillary acidic protein

Summary

Gene Symbol

GFAP

Organism

Homo sapiens (human)

External Links

NCBI Gene

2670

PubChem

2670

Alliance of Genome Resources

HGNC:4235

JoGo

GFAP

TogoVar

GFAP

Annotation

Keyword

3D-structure
Alternative splicing
Citrullination
Coiled coil
Cytoplasm
Direct protein sequencing
Disease variant
Intermediate filament
Leukodystrophy
Methylation
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A1X7SBR3
P14136

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
intracellular protein transport	IEA
gene expression	IEA
positive regulation of Schwann cell proliferation	IEA
negative regulation of neuron projection development	IEA
astrocyte development	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell population proliferation [inference]

glial cell proliferation [inference]

Schwann cell proliferation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

astrocyte differentiation [inference]

Bergmann glial cell differentiation

cell development [inference]

glial cell development [inference]

astrocyte development

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection regeneration

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

supramolecular fiber organization [inference]

intermediate filament organization

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

neuron projection regeneration

cell development [inference]

glial cell development [inference]

astrocyte development

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

astrocyte differentiation [inference]

Bergmann glial cell differentiation

cell development [inference]

glial cell development [inference]

astrocyte development

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

neuron projection regeneration

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

D-aspartate transport [inference]

D-aspartate import across plasma membrane

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

D-amino acid transport [inference]

D-aspartate transport [inference]

D-aspartate import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

D-aspartate transport [inference]

D-aspartate import across plasma membrane

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

D-amino acid transport [inference]

D-aspartate transport [inference]

D-aspartate import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport [inference]

D-aspartate import across plasma membrane

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

D-amino acid transport [inference]

D-aspartate transport [inference]

D-aspartate import across plasma membrane

protein transport [inference]

intracellular protein transport

import into cell [inference]

amino acid import across plasma membrane [inference]

D-aspartate import across plasma membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of chaperone-mediated autophagy

regulation of protein catabolic process [inference]

regulation of chaperone-mediated autophagy

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of chaperone-mediated autophagy

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of chaperone-mediated autophagy

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of chaperone-mediated autophagy

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of chaperone-mediated autophagy

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of localization [inference]

regulation of transport [inference]

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of chaperone-mediated autophagy

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of glial cell proliferation [inference]

regulation of Schwann cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

regulation of protein-containing complex assembly

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation [inference]

positive regulation of Schwann cell proliferation

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasm	IDA	12355421
cytoplasm	IBA
lysosome	ISS
cytosol	TAS
intermediate filament	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection

plasma membrane bounded cell projection [inference]

glial cell projection [inference]

astrocyte projection [inference]

astrocyte end-foot

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton

cell body

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of lysosomal membrane

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

Displaying **all 5** entries
GO Term	Evidence Code	PMID
integrin binding	IEA
structural constituent of cytoskeleton	IBA
protein binding	IPI	16189514 17500595 25416956 25910212 26871637 27229929 29892012 31515488 32296183 32814053 33961781 34819669
kinase binding	IEA
identical protein binding	IPI	25416956 25910212 32296183