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gamma-glutamyl carboxylase
Summary
- Gene Symbol
-
- GGCX
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Lyase
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8I5QJA4 |
|
| P38435 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood coagulation | ||
| peptidyl-glutamic acid carboxylation |
|
|
| protein modification process | ||
| vitamin K metabolic process | ||
| vitamin K metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum lumen | ||
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane | ||
| membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| gamma-glutamyl carboxylase activity | ||
| gamma-glutamyl carboxylase activity | ||
| gamma-glutamyl carboxylase activity | ||
| vitamin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- vitamin k-dependent gamma-carboxylase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
- V: Defense mechanisms
| Gene Ontology |
|---|
| gamma-glutamyl carboxylase activity |
| vitamin binding |
| InterPro |
|---|
| HTTM |
| Vitamin K-dependent gamma-carboxylase |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112173 | combined deficiency of vitamin K-dependent clotting factors 1 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2677 | Xenbase:XB-GENE-949715 | ||
| 56316 | Xenbase:XB-GENE-949715 | MOUSE50974 | |
| 81716 | RATNO31989 | ||
| 281190 | BOVIN02578 | ||
| 443129 | SHEEP13745 | ||
| 459364 | PANTR28061 | ||
| 695628 | MACMU07732 | ||
| 100030057 | MONDO06286 | ||
| 100067312 | HORSE09521 | ||
| 100077833 | ORNAN03059 |
