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mannoside acetylglucosaminyltransferase 5, isoenzyme B

Summary

Gene Symbol

Mgat5b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

268510

KEGG Gene ID

mmu:268510

PubChem

268510

Alliance of Genome Resources

MGI:3606200

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q765H6	Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B GlcNAc-T Vb Mannoside acetylglucosaminyltransferase 5B N-acetylglucosaminyl-transferase Vb N-acetylglucosaminyltransferase IX

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IDA	16413118
protein N-linked glycosylation	IBA
protein O-linked glycosylation via serine	ISO
protein O-linked glycosylation via serine	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein O-linked glycosylation [inference]

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
Golgi apparatus	IDA	16413118
Golgi apparatus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	ISO
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IDA	16413118
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IBA
manganese ion binding	ISO
manganese ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 3** entries
Gene Ontology
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
protein N-linked glycosylation
transferase activity

Displaying 1 entry
InterPro
Glycosyltransferase family 18

KEGG BRITE Database

Orthology

K09661

Name

mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]

References

12941944

Reactions

Displaying **all 6** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07624	2.4.1.-	G10219AA	G83717YJ
R05991	2.4.1.155	G29011JC	G20030CU
R07622	2.4.1.-	G39213VZ	G10219AA
R07625	2.4.1.-	G88380UG	G83717YJ
R07623	2.4.1.-	G39213VZ	G88380UG
R07621	2.4.1.-	G85856KC	G56868BH

Rhea

RHEA:16921

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.155

PMID

Ortholog

Displaying entries **1 - 10** of **112** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	4249	WB:WBGene00001627
Caenorhabditis elegans	65271	WB:WBGene00001627
Caenorhabditis elegans	107895	WB:WBGene00001627
Homo sapiens	146664	Xenbase:XB-GENE-987716	HUMAN36541
Xenopus tropicalis	172360	Xenbase:XB-GENE-987716
Xenopus tropicalis	268510	Xenbase:XB-GENE-987716
Rattus norvegicus	303693	Xenbase:XB-GENE-987716	RATNO00803
Canis lupus familiaris	483337		CANLF18409
Macaca mulatta	708299		MACMU15916
Caenorhabditis elegans	724006	WB:WBGene00001627

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Acknowledgements