GlyCosmos Portal

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytosol	IEA
eukaryotic translation initiation factor 2 complex	ISS	31836389
eukaryotic translation initiation factor 2 complex	ISO
eukaryotic translation initiation factor 2 complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

eukaryotic translation initiation factor 2 complex

cellular anatomical entity [inference]

cell junction [inference]

synapse

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
tRNA binding	IBA
translation initiation factor activity	ISS
translation initiation factor activity	ISO
translation initiation factor activity	IBA
GTPase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

methionyl-initiator methionine tRNA binding

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding

translation initiation factor activity

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

eukaryotic translation initiation factor 2 subunit

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
GTP binding
formation of translation preinitiation complex
hydrolase activity
nucleotide binding
selenocysteine insertion sequence binding
selenocysteine metabolic process

Displaying **all 8** entries
InterPro
Initiation factor eIF2 gamma, C-terminal
Initiation factor eIF2 gamma, GTP-binding domain
Initiation factor eIF2 gamma, domain 2
P-loop containing nucleoside triphosphate hydrolase
Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Translation elongation factor EFTu-like, domain 2
Translation protein, beta-barrel domain superfamily
Translational (tr)-type GTP-binding domain