GlyCosmos Portal

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
translation factor activity, RNA binding	ISO ISS
GTPase activity	IEA
translation initiation factor activity	IBA ISO ISS
tRNA binding	IBA
methionyl-initiator methionine tRNA binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

methionyl-initiator methionine tRNA binding

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding

translation initiation factor activity

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Translation initiation factor

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
GTP binding
formation of translation preinitiation complex
hydrolase activity
nucleotide binding
selenocysteine insertion sequence binding
selenocysteine metabolic process

Displaying **all 8** entries
InterPro
Initiation factor eIF2 gamma, C-terminal
Initiation factor eIF2 gamma, GTP-binding domain
Initiation factor eIF2 gamma, domain 2
P-loop containing nucleoside triphosphate hydrolase
Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Translation elongation factor EFTu-like, domain 2
Translation protein, beta-barrel domain superfamily
Translational (tr)-type GTP-binding domain

Rhea

RHEA:19669

H₂O + GTP

H⁺ + phosphate + GDP

Enzyme

PMID

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060801	MEHMO syndrome	Alliance of Genome Resources
DOID:10579	leukodystrophy	Alliance of Genome Resources
DOID:4194	glucose metabolism disease	Alliance of Genome Resources
DOID:9406	hypopituitarism	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **165** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1968		HGNC:3267	HUMAN100057
Drosophila melanogaster	41843		FB:FBgn0263740
Caenorhabditis elegans	171792		WB:WBGene00021466
Homo sapiens	255308		HGNC:43863
Rattus norvegicus	299027	10116_1:0056ee	RGD:1561279	RATNO45142
Danio rerio	327341		ZFIN:ZDB-GENE-030131-5552	DANRE26379
Pan troglodytes	455519			PANTR16451
Pan troglodytes	465540			PANTR16451
Xenopus tropicalis	496946		Xenbase:XB-GENE-986363
Bos taurus	512350			BOVIN37328

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements