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mannoside acetylglucosaminyltransferase 4, isoenzyme A

Summary

Gene Symbol

Mgat4a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

269181

KEGG Gene ID

mmu:269181

PubChem

269181

Alliance of Genome Resources

MGI:2662992

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Glycoprotein
Glycosyltransferase
Golgi apparatus
Metal-binding
Phosphoprotein
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q812G0	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein glycosylation	ISO
protein N-linked glycosylation	IGI	20015870
protein N-linked glycosylation	IBA
N-glycan processing	IDA	16377570
glyoxylate metabolic process	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
extracellular region	IEA
peroxisome	ISS
endoplasmic reticulum	IBA
endoplasmic reticulum-Golgi intermediate compartment	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IDA	20015870
acetylglucosaminyltransferase activity	IBA
alanine-glyoxylate transaminase activity	ISS
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	ISO
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	IDA	16377570

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

alanine-glyoxylate transaminase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha-1 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
acetylglucosaminyltransferase activity
protein N-linked glycosylation

Displaying 1 entry
InterPro
Glycosyl transferase family 54

KEGG BRITE Database

Orthology

K00738

Name

alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05987	2.4.1.145	G39213VZ	G29011JC

Rhea

RHEA:16057

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.145

PMID

Ortholog

Displaying entries **91 - 100** of **103** in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113900947	BOBOX19032
Podarcis muralis	114596371	PODMU20090
Salmo trutta	115155869	SALTR09574
Salmo trutta	115161257	SALTR14758
Salarias fasciatus	115403195	SALFA50478
Gadus morhua	115533027	GADMO31501
Sparus aurata	115587913	SPAAU28893
Strigops habroptila	115604170	STRHB00556
Chelonoidis abingdonii	116839539	CHEAB13790
Rhinolophus ferrumequinum	117033458	RHIFE24196

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements