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reticulon 4 receptor-like 2

Summary

Gene Symbol

Rtn4rl2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

269295

PubChem

269295

Alliance of Genome Resources

MGI:2669796

Annotation

Keyword

Cell membrane
Cell projection
Disulfide bond
GPI-anchor
Leucine-rich repeat
Receptor
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7M6Z0	Nogo receptor-like 3 Nogo-66 receptor homolog 1 Nogo-66 receptor-related protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	ISO ISS
corpus callosum development	IMP	27339102
axon regeneration	TAS	14664809
negative regulation of neuron projection development	IMP ISO ISS	22406547

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection regeneration [inference]

axon regeneration

axon development [inference]

axon regeneration

developmental process [inference]

anatomical structure development [inference]

corpus callosum development

regeneration [inference]

neuron projection regeneration [inference]

axon regeneration

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

response to axon injury [inference]

axon regeneration

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
side of membrane	IEA
neuron projection	ISO ISS
cell surface	ISO ISS
dendrite	IEA
axon	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

external encapsulating structure [inference]

extracellular matrix

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

perikaryon

side of membrane

external side of plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
signaling receptor activity	IBA ISO ISS

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

reticulon-4 receptor-like 2

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	311169	10116_1:00167f	RGD:727797	RATNO26113
Homo sapiens	349667		HGNC:23053	HUMAN06023
Danio rerio	403307		ZFIN:ZDB-GENE-040310-4
Danio rerio	403309		ZFIN:ZDB-GENE-040310-2
Pan troglodytes	466587			PANTR02925
Bos taurus	529030			BOVIN07688
Macaca mulatta	704489			MACMU09851
Equus caballus	100066806			HORSE05678
Callithrix jacchus	100415515			CALJA03883
Pongo abelii	100435919			PONAB02622