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solute carrier family 28 (sodium-coupled nucleoside transporter), member 2

Summary

Gene Symbol

Slc28a2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

269346

PubChem

269346

Alliance of Genome Resources

MGI:1913105

Annotation

Keyword

Cell membrane
Phosphoprotein
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
O88627	Concentrative nucleoside transporter 2 Na(+)/nucleoside cotransporter 2 Sodium-coupled nucleoside transporter 2 Sodium/purine nucleoside cotransporter Solute carrier family 28 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
retina homeostasis	ISO
retina homeostasis	IBA
neurotransmitter transport	ISO
purine nucleoside transmembrane transport	ISO
purine nucleoside transmembrane transport	TAS	10721696

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell surface

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

nucleoside transmembrane transport

purine nucleoside transmembrane transport

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell surface

establishment of localization [inference]

transport [inference]

neurotransmitter transport

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

nucleoside transmembrane transport

purine nucleoside transmembrane transport

organic substance transport [inference]

nucleobase transport [inference]

purine nucleobase transport [inference]

purine nucleobase transmembrane transport

nucleobase-containing compound transport [inference]

nucleoside transport [inference]

pyrimidine nucleoside transport [inference]

uridine transport

nucleoside transmembrane transport

purine nucleoside transmembrane transport

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

carbohydrate derivative transport [inference]

nucleoside transport [inference]

pyrimidine nucleoside transport [inference]

uridine transport

nucleoside transmembrane transport

purine nucleoside transmembrane transport

nitrogen compound transport [inference]

nucleobase transport [inference]

purine nucleobase transport [inference]

purine nucleobase transmembrane transport

nucleobase-containing compound transport [inference]

nucleoside transport [inference]

pyrimidine nucleoside transport [inference]

uridine transport

nucleoside transmembrane transport

purine nucleoside transmembrane transport

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell surface

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS	10721696
plasma membrane	ISO
plasma membrane	IBA
vesicle membrane	ISO
apicolateral plasma membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane

plasma membrane region [inference]

apicolateral plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
neurotransmitter transmembrane transporter activity	ISO
nucleoside transmembrane transporter activity	ISO
purine nucleobase transmembrane transporter activity	ISO
nucleoside:sodium symporter activity	ISO
nucleoside:sodium symporter activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

neurotransmitter transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase transmembrane transporter activity [inference]

purine nucleobase transmembrane transporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

pyrimidine nucleobase transmembrane transporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleoside transmembrane transporter activity

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

purine nucleoside transmembrane transporter activity

pyrimidine nucleoside transmembrane transporter activity [inference]

uridine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

carbohydrate derivative transmembrane transporter activity [inference]

nucleoside transmembrane transporter activity

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

purine nucleoside transmembrane transporter activity

pyrimidine nucleoside transmembrane transporter activity [inference]

uridine transmembrane transporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
F: Nucleotide transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
nucleoside transmembrane transport
nucleoside transmembrane transporter activity
purine-specific nucleoside
pyrimidine nucleoside transport
pyrimidine- and adenosine-specific

Displaying **all 4** entries
InterPro
Concentrative nucleoside transporter C-terminal domain
Concentrative nucleoside transporter N-terminal domain
Concentrative nucleoside transporter
Nucleoside transporter/FeoB GTPase, Gate domain

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9153	Xenbase:XB-GENE-965932	HUMAN22872
Xenopus tropicalis	9154	Xenbase:XB-GENE-965932
Rattus norvegicus	60423		RATNO26698
Drosophila melanogaster	64078	FB:FBgn0033371
Drosophila melanogaster	114304	FB:FBgn0033371
Xenopus tropicalis	116642	Xenbase:XB-GENE-965932
Xenopus tropicalis	269346	Xenbase:XB-GENE-965932
Xenopus tropicalis	381417	Xenbase:XB-GENE-965932
Xenopus tropicalis	434203	Xenbase:XB-GENE-965932
Pan troglodytes	453400		PANTR10225