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serine incorporator 3

Summary

Gene Symbol

Serinc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

26943

PubChem

26943

Alliance of Genome Resources

MGI:1349457

Annotation

Keyword

Antiviral defense
Cell membrane
Glycoprotein
Golgi apparatus
Innate immunity
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QZI9	Axotomy-induced glyco/Golgi protein 1 Axotomy-induced glycoprotein 1 Membrane protein TMS-1 Tumor differentially expressed protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
detection of virus	ISO
plasma membrane phospholipid scrambling	ISS
innate immune response	ISO
defense response to virus	ISO
antiviral innate immune response	ISS

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

antiviral innate immune response

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane phospholipid scrambling

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

detection of virus

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

innate immune response

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus

antiviral innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus

antiviral innate immune response

immune response [inference]

innate immune response

antiviral innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

detection of virus

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

innate immune response

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus

antiviral innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

detection of virus

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

innate immune response

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus

antiviral innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
Golgi apparatus	IDA	12486168
plasma membrane	IDA	10637174
membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying 1 entry
GO Term	Evidence Code	PMID
phospholipid scramblase activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity [inference]

phospholipid scramblase activity

intramembrane lipid transporter activity [inference]

phospholipid scramblase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

serine incorporator

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Serine incorporator/TMS membrane protein

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements