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glycerol kinase 2

Summary

Gene Symbol

GK2

Aliases

GKTA

Organism

Homo sapiens (human)

External Links

NCBI Gene

2712

HGNC

4291

KEGG Gene ID

hsa:2712

PubChem

2712

Alliance of Genome Resources

HGNC:4291

Annotation

Keyword

ATP-binding
Cytoplasm
Glycerol metabolism
Kinase
Mitochondrion outer membrane
Reference proteome
Spermatogenesis
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A140VKG0
Q14410	ATP:glycerol 3-phosphotransferase 2 Glycerol kinase, testis specific 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
triglyceride metabolic process	IBA
spermatogenesis	ISS
sperm mitochondrial sheath assembly	ISS
phosphorylation	IBA
glycerol catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alditol metabolic process [inference]

glycerol metabolic process

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alditol metabolic process [inference]

glycerol metabolic process

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

carbohydrate derivative metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

cellular process involved in reproduction in multicellular organism [inference]

sperm mitochondrial sheath assembly

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glycerol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

sperm mitochondrial sheath assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

sperm mitochondrial sheath assembly

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

sperm motility [inference]

flagellated sperm motility

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial outer membrane	ISS
sperm midpiece	IDA	28852571
mitochondrion	IBA
sperm mitochondrial sheath	ISS
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycerol kinase activity	IBA NAS	7987308
ATP binding	IEA
protein binding	IPI	28852571

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

glycerol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

glycerol kinase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00864

Name

glycerol kinase [EC:2.7.1.30]

References

14756771

Rhea

glycerol + ATP

H⁺ + ADP + sn-glycerol 3-phosphate

Enzyme

2.7.1.30

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060363	glycerol kinase deficiency	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006643
Gene Name: glycerol kinase 2

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	173747	WB:WBGene00020007
Drosophila melanogaster	36282	FB:FBgn0033673
Drosophila melanogaster	38221	FB:FBgn0035266
Drosophila melanogaster	43913	FB:FBgn0025592
Danio rerio	100136866	ZFIN:ZDB-GENE-080204-72
Astyanax mexicanus	103032412		ASTMX11896
Ictalurus punctatus	108259045		ICTPU21131
Ictalurus punctatus	108266598		ICTPU31421
Electrophorus electricus	113575342		ELEEL16789
Electrophorus electricus	113590738		ELEEL45372

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024