ALF transcription elongation factor 4

Summary
Gene Symbol
  • AFF4
Organism
Homo sapiens (human)
NCBI Gene
27125
PubChem
27125
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Chromosomal rearrangement
  • Direct protein sequencing
  • Disease variant
  • Dwarfism
  • Isopeptide bond
  • Nucleus
  • Obesity
  • Phosphoprotein
  • Proto-oncogene
  • Reference proteome
  • Transcription regulation
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q9UHB7
  • ALL1-fused gene from chromosome 5q31 protein
  • Major CDK9 elongation factor-associated protein
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
AF4/FMR2 family member
Functional Category
  • E: Amino acid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
regulation of gene expression
Displaying all 2 entries
InterPro
AF4/FMR2 family
AF4/FMR2, C-terminal homology domain
Disease
Disease Ontology
Displaying all 3 entries
DO ID Disease Name Source
DOID:8923 skin melanoma
DOID:9256 colorectal cancer
DOID:9352 type 2 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024