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NFU1 iron-sulfur cluster scaffold

Summary

Gene Symbol

NFU1

Organism

Homo sapiens (human)

External Links

NCBI Gene

27247

PubChem

27247

Alliance of Genome Resources

HGNC:16287

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Disease variant
Iron-sulfur
Mitochondrion
Primary mitochondrial disease
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UMS0	HIRA-interacting protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein maturation by [2Fe-2S] cluster transfer	IDA	27538573
protein maturation by [4Fe-4S] cluster transfer	IBA
iron-sulfur cluster assembly	IDA	12886008 28906594

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein maturation by iron-sulfur cluster transfer [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

iron-sulfur cluster assembly

primary metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein maturation by iron-sulfur cluster transfer [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein maturation by iron-sulfur cluster transfer [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein maturation by iron-sulfur cluster transfer [inference]

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

iron-sulfur cluster assembly

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

metallo-sulfur cluster assembly [inference]

iron-sulfur cluster assembly

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	IDA	12886008
mitochondrial matrix	TAS
nucleoplasm	IDA
cytosol	IDA	12886008 12915448
mitochondrion	HTP IBA IDA	12886008 34800366

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
2 iron, 2 sulfur cluster binding	IDA	27538573
iron ion binding	IDA	12886008
protein binding	IPI	11342215 12915448 22190034 25416956 26702583 27532772 32296183
4 iron, 4 sulfur cluster binding	IBA IDA	12886008 28906594