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protocadherin 17

Summary

Gene Symbol

PCDH17

Organism

Homo sapiens (human)

External Links

NCBI Gene

27253

PubChem

27253

Alliance of Genome Resources

HGNC:14267

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell adhesion
Cell membrane
Glycoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O14917	Protocadherin-68

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell adhesion	IBA
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
adult behavior	IEA
negative regulation of synaptic transmission	IEA
synaptic membrane adhesion	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

presynaptic active zone assembly

presynaptic active zone organization [inference]

presynaptic active zone assembly

multicellular organismal process [inference]

behavior [inference]

adult behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

regulation of localization [inference]

regulation of synaptic vesicle clustering

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
presynaptic membrane	IEA
postsynaptic membrane	IEA
glutamatergic synapse	IEA
GABA-ergic synapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
protein binding	IPI	19945174 32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protocadherin-19

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 4** entries
InterPro
Cadherin conserved site
Cadherin, N-terminal
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	27253	Xenbase:XB-GENE-480220
Mus musculus	219228	Xenbase:XB-GENE-480220	MOUSE13676
Rattus norvegicus	306055		RATNO09452
Pan troglodytes	467373		PANTR07852
Danio rerio	561336		DANRE02377
Macaca mulatta	695637		MACMU16314
Monodelphis domestica	100010317		MONDO31354
Equus caballus	100051691		HORSE12791
Ornithorhynchus anatinus	100080331		ORNAN17037
Taeniopygia guttata	100220520		TAEGU11181