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Glycan Structure Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
glutamate-cysteine ligase catalytic subunit
Summary
- Gene Symbol
-
- GCLC
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Disease variant
- Glutathione biosynthesis
- Hereditary hemolytic anemia
- Ligase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to human chorionic gonadotropin | ||
| cell redox homeostasis | ||
| negative regulation of DNA-templated transcription | ||
| negative regulation of transcription, DNA-templated | ||
| response to arsenic-containing substance |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| cytosol | ||
| glutamate-cysteine ligase complex | ||
| glutamate-cysteine ligase complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| magnesium ion binding | ||
| glutamate-cysteine ligase activity | ||
| glutamate-cysteine ligase activity | ||
| glutamate-cysteine ligase activity | ||
| protein binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111681 | congenital nonspherocytic hemolytic anemia 7 | |
| DOID:1485 | cystic fibrosis | |
| DOID:583 | hemolytic anemia | |
| DOID:5844 | myocardial infarction |
