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serine racemase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

27364

PubChem

27364

Alliance of Genome Resources

MGI:1351636

Annotation

Keyword

ATP-binding
Allosteric enzyme
Alternative splicing
Calcium
Direct protein sequencing
Isomerase
Lyase
Magnesium
Manganese
Metal-binding
Phosphoprotein
Pyridoxal phosphate
Reference proteome
S-nitrosylation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QZX7	D-serine ammonia-lyase D-serine dehydratase L-serine ammonia-lyase L-serine dehydratase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
L-serine metabolic process	ISO	11054547
L-serine metabolic process	IDA	10557334 12021263 15710237 16517698
serine family amino acid metabolic process	IDA	15536068
response to xenobiotic stimulus	IEA
response to organic cyclic compound

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process

L-serine metabolic process

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

D-amino acid metabolic process [inference]

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-serine metabolic process

D-serine biosynthetic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

D-serine biosynthetic process

D-amino acid biosynthetic process [inference]

D-serine biosynthetic process

monocarboxylic acid biosynthetic process [inference]

pyruvate biosynthetic process

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to organic cyclic compound

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IBA
cytoplasm	IEA
neuronal cell body	ISO
neuronal cell body	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell body [inference]

neuronal cell body

apical part of cell

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	ISO
magnesium ion binding	IBA
magnesium ion binding	IEA
L-serine ammonia-lyase activity	ISO
L-serine ammonia-lyase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-nitrogen lyase activity [inference]

ammonia-lyase activity [inference]

isomerase activity [inference]

racemase and epimerase activity [inference]

racemase and epimerase activity, acting on amino acids and derivatives [inference]

racemase activity, acting on amino acids and derivatives [inference]

amino-acid racemase activity [inference]

binding [inference]

protein binding

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

glycine binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

carboxylic acid binding [inference]

amino acid binding [inference]

glycine binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

glycine binding

metal ion binding [inference]

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dehydratase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
L-serine ammonia-lyase activity
L-serine catabolic process
isoleucine biosynthetic process
pyridoxal phosphate binding
threonine catabolic process
threonine deaminase activity

Displaying **all 3** entries
InterPro
Serine/threonine dehydratase, pyridoxal-phosphate-binding site
Tryptophan synthase beta chain-like, PALP domain superfamily
Tryptophan synthase beta chain-like, PALP domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	27364	Xenbase:XB-GENE-954863
Homo sapiens	63826		HUMAN30747
Rattus norvegicus	303306		RATNO01304
Bos taurus	525340		BOVIN12514
Macaca mulatta	703426		MACMU14842
Pan troglodytes	747543		PANTR13209
Monodelphis domestica	100018989		MONDO15953
Equus caballus	100060209		HORSE02979
Ornithorhynchus anatinus	100078533		ORNAN08747
Taeniopygia guttata	100219482		TAEGU07482

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements