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ATP-binding cassette, sub-family A member 3

Summary

Gene Symbol

Abca3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

27410

PubChem

27410

Alliance of Genome Resources

MGI:1351617

Annotation

Keyword

ATP-binding
Cytoplasmic vesicle
Disulfide bond
Endosome
Glycoprotein
Lipid transport
Lysosome
Proteomics identification
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8R420	ATP-binding cassette sub-family A member 3 Xenobiotic-transporting ATPase ABCA3
Q6AXE3
Q3TN91

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **26 - 30** of 33 in total

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GO Term	Evidence Code	PMID
organelle assembly	IMP	17540762
intermembrane lipid transfer	IEA
regulation of phosphatidylcholine metabolic process	ISS
regulation of phosphatidylcholine metabolic process	ISO
positive regulation of phospholipid efflux	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

transmembrane transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly

cellular component assembly [inference]

organelle assembly

membrane organization [inference]

regulation of membrane lipid distribution [inference]

lipid translocation

intermembrane lipid transfer

export from cell [inference]

xenobiotic export from cell

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

lung development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

chemical homeostasis [inference]

lipid homeostasis [inference]

phospholipid homeostasis

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

localization [inference]

establishment of localization [inference]

transport

xenobiotic transport

transmembrane transport [inference]

organic substance transport [inference]

lipid transport

organophosphate ester transport [inference]

phospholipid transport

export from cell [inference]

xenobiotic export from cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of lipid biosynthetic process

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylcholine metabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of phosphatidylcholine metabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of lipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylcholine metabolic process

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of phospholipid transport [inference]

regulation of phospholipid efflux [inference]

positive regulation of phospholipid efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

regulation of lipid localization [inference]

regulation of lipid transport

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of phospholipid transport [inference]

regulation of phospholipid efflux [inference]

positive regulation of phospholipid efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport

positive regulation of phospholipid efflux

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylcholine metabolic process

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of protein oligomerization [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of protein homooligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of protein oligomerization [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of protein homooligomerization [inference]

positive regulation of protein homooligomerization

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein oligomerization [inference]

positive regulation of protein homooligomerization

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
lysosomal membrane	IEA
late endosome	ISS
late endosome	ISO
plasma membrane	ISO
membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

secretory granule membrane [inference]

lamellar body membrane

alveolar lamellar body membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

secretory granule membrane [inference]

lamellar body membrane

alveolar lamellar body membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

secretory vesicle [inference]

secretory granule [inference]

lamellar body

alveolar lamellar body

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

secretory vesicle [inference]

secretory granule [inference]

lamellar body

alveolar lamellar body

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

secretory vesicle [inference]

secretory granule [inference]

lamellar body

alveolar lamellar body

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
lipid transporter activity	IBA
ATP binding	IEA
ABC-type xenobiotic transporter activity	ISS
ABC-type xenobiotic transporter activity	ISO
ATP hydrolysis activity	ISS