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alpha glucosidase

Summary

Gene Symbol

GAA

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 280798
KEGG Gene ID: bta:280798
PubChem: 280798

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Membrane
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9MYM4	Acid maltase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
vacuolar sequestering
cardiac muscle contraction
glycogen catabolic process	IEA	30032202
aorta development
diaphragm contraction

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

maintenance of location in cell [inference]

vacuolar sequestering

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

skeletal muscle contraction [inference]

involuntary skeletal muscle contraction [inference]

diaphragm contraction

cardiac muscle contraction

respiratory system process [inference]

diaphragm contraction

nervous system process [inference]

neuromuscular process [inference]

behavior [inference]

locomotory behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

heart morphogenesis

anatomical structure development [inference]

blood vessel development [inference]

artery development [inference]

aorta development

tissue development

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

localization [inference]

maintenance of location [inference]

maintenance of location in cell [inference]

vacuolar sequestering

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction

regulation of biological quality [inference]

regulation of the force of heart contraction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
autolysosome lumen
lysosomal membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

autolysosome lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
alpha-1,4-glucosidase activity	IEA	30032202
maltose alpha-glucosidase activity
carbohydrate binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

alpha-glucosidase activity [inference]

alpha-1,4-glucosidase activity

maltose alpha-glucosidase activity

binding [inference]

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha glucosidase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-glucosidase activity
catalytic activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 7** entries
InterPro
Galactose mutarotase-like domain superfamily
Glycoside hydrolase family 31, N-terminal domain
Glycoside hydrolase family 31, TIM barrel domain
Glycoside hydrolase superfamily
Glycosyl hydrolase family 31, C-terminal domain
Glycosyl hydrolase, all-beta
Glycosyl hydrolases family 31, active site

KEGG BRITE Database

Orthology

K12316

Name

lysosomal alpha-glucosidase [EC:3.2.1.20]

References

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2548			HUMAN36786
Mus musculus	14387			MOUSE04476
Rattus norvegicus	367562			RATNO03032
Pan troglodytes	454940			PANTR15614
Canis lupus familiaris	483352			CANLF18375
Macaca mulatta	712054			MACMU16074
Monodelphis domestica	100030818			MONDO13604
Equus caballus	100056675			HORSE03618
Pongo abelii	100173365			PONAB12637
Taeniopygia guttata	100227842			TAEGU06897

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024