GlyCosmos Portal

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GO Term	Evidence Code	PMID
intermediate-density lipoprotein particle	IEA	30032202
high-density lipoprotein particle
chylomicron
extracellular exosome
multivesicular body, internal vesicle

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

triglyceride-rich plasma lipoprotein particle [inference]

chylomicron

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

multivesicular body, internal vesicle

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

multivesicular body, internal vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

multivesicular body, internal vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

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GO Term	Evidence Code	PMID
amyloid-beta binding	IEA	30032202
phospholipid binding
heparin binding
lipid binding	IEA	22301074
identical protein binding

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

sterol transporter activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

lipoprotein particle receptor binding [inference]

identical protein binding

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

lipid binding

phospholipid binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

phosphatidylcholine-sterol O-acyltransferase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

phosphatidylcholine-sterol O-acyltransferase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Apolipoprotein E

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying entries **11 - 14** of 14 in total

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Gene Ontology
regulation of intestinal cholesterol absorption
reverse cholesterol transport
triglyceride homeostasis
very-low-density lipoprotein particle remodeling

Displaying 1 entry
InterPro
Apolipoprotein A/E

Ortholog

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	348	HUMAN44284
Mus musculus	11816	MOUSE53726
Rattus norvegicus	25728	RATNO16263
Danio rerio	30314	DANRE10814
Sus scrofa	397576	PIGXX28040
Pan troglodytes	449586	PANTR18605
Canis lupus familiaris	476438	CANLF00952
Danio rerio	553587	DANRE16364
Macaca mulatta	714623	MACMU19030
Takifugu rubripes	777965	TAKRU05082

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements