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cytochrome b-245 beta chain

Summary

Gene Symbol

CYBB

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281112
PubChem: 281112

Annotation

Keyword

Cell membrane
Electron transport
FAD
Glycoprotein
Heme
Isopeptide bond
NADP
Oxidoreductase
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation
Voltage-gated channel

Proteins

Displaying 1 entry
UniProt	Protein Name
O46522	CGD91-phox Cytochrome b(558) subunit beta Heme-binding membrane glycoprotein gp91phox Neutrophil cytochrome b 91 kDa polypeptide gp91-1 gp91-phox p22 phagocyte B-cytochrome

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
superoxide anion generation	IEA	30032202
ion transmembrane transport
superoxide metabolic process
defense response	IEA	30032202
innate immune response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

metabolic process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

cellular process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
NADPH oxidase complex	IEA	30032202
plasma membrane	IEA	30032202
membrane raft
monoatomic ion channel complex
lysosome

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

NADPH oxidase complex

transmembrane transporter complex [inference]

monoatomic ion channel complex

catalytic complex [inference]

oxidoreductase complex [inference]

NADPH oxidase complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
superoxide-generating NAD(P)H oxidase activity	IEA	30032202
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

superoxide-generating NAD(P)H oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Respiratory burst

Functional Category

C: Energy production and conversion
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ferric-chelate reductase activity
oxidoreductase activity

Displaying **all 6** entries
InterPro
FAD-binding 8
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Ferric reductase transmembrane component-like domain
Ferric reductase, NAD binding domain
Riboflavin synthase-like beta-barrel

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	1536		HUMAN100170
Mus musculus	13058		MOUSE66390
Rattus norvegicus	66021		RATNO45304
Sus scrofa	397108	9823_0:004b06	PIGXX37152
Takifugu rubripes	445888		TAKRU48429
Pan troglodytes	465566		PANTR45745
Canis lupus familiaris	491825		CANLF19678
Macaca mulatta	696542		MACMU47192
Monodelphis domestica	100017914		MONDO21154
Ovis aries	100036757	9940_0:005316	SHEEP19641

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements