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cytochrome b-245 beta chain

Summary

Gene Symbol

CYBB

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281112
PubChem: 281112

Annotation

Keyword

Cell membrane
Electron transport
FAD
Glycoprotein
Heme
Isopeptide bond
NADP
Oxidoreductase
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation
Voltage-gated channel

Proteins

Displaying 1 entry
UniProt	Protein Name
O46522	CGD91-phox Cytochrome b(558) subunit beta Heme-binding membrane glycoprotein gp91phox Neutrophil cytochrome b 91 kDa polypeptide gp91-1 gp91-phox p22 phagocyte B-cytochrome

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
monoatomic ion transmembrane transport
inflammatory response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

metabolic process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

cellular process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
NADPH oxidase complex	IEA	30032202
plasma membrane	IEA	30032202
membrane raft
monoatomic ion channel complex
lysosome

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

NADPH oxidase complex

transmembrane transporter complex [inference]

monoatomic ion channel complex

catalytic complex [inference]

oxidoreductase complex [inference]

NADPH oxidase complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
superoxide-generating NAD(P)H oxidase activity	IEA	30032202
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

superoxide-generating NAD(P)H oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Respiratory burst

Functional Category

C: Energy production and conversion
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ferric-chelate reductase activity
oxidoreductase activity

Displaying **all 6** entries
InterPro
FAD-binding 8
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Ferric reductase transmembrane component-like domain
Ferric reductase, NAD binding domain
Riboflavin synthase-like beta-barrel

Ortholog

Displaying entries **11 - 20** of 89 in total

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Species	Gene ID	Orthologous MAtrix
Equus caballus	100050132	HORSE44704
Ornithorhynchus anatinus	100082988	ORNAN09938
Taeniopygia guttata	100225149	TAEGU11901
Callithrix jacchus	100415466	CALJA47828
Pongo abelii	100459132	PONAB37955
Ailuropoda melanoleuca	100468223	AILME18599
Meleagris gallopavo	100543754	MELGA01360
Nomascus leucogenys	100605123	NOMLE39070
Loxodonta africana	100655878	LOXAF01875
Oreochromis niloticus	100705711	ORENI44866

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements