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desmocollin 1

Summary

Gene Symbol

DSC1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281127
PubChem: 281127

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6QR67
Q01107	Desmosomal glycoprotein 2/3

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell morphogenesis
synapse assembly
adherens junction organization
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction organization [inference]

synapse organization [inference]

synapse assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

Displaying entries **6 - 10** of 13 in total

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GO Term	Evidence Code	PMID
neuron projection
adherens junction
intercalated disc
lamellipodium
catenin complex

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

cell projection [inference]

plasma membrane bounded cell projection [inference]

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
beta-catenin binding
calcium ion binding	IEA	22301074 30032202
cadherin binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Cadherin conserved site
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily

Ortholog

Displaying entries **61 - 70** of 99 in total

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Species	Gene ID	Orthologous MAtrix
Aotus nancymaae	105713476	AOTNA17171
Propithecus coquereli	105820139	PROCO14481
Dipodomys ordii	105984620	DIPOR04489
Equus asinus asinus	106831814	EQUAS10412
Sinocyclocheilus grahami	107570028	SINGR96030
Sinocyclocheilus grahami	107588868	SINGR44310
Kryptolebias marmoratus	108239669	KRYMA14912
Ictalurus punctatus	108258010	ICTPU20290
Rhinopithecus bieti	108519201	RHIBE21996
Cyprinus carpio carpio	109051955	CYPCA102857