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desmocollin 1

Summary

Gene Symbol

DSC1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281127
PubChem: 281127

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6QR67
Q01107	Desmosomal glycoprotein 2/3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cell morphogenesis
synapse assembly
adherens junction organization
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction organization [inference]

synapse organization [inference]

synapse assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
membrane
desmosome	IEA	30032202
postsynaptic density
postsynaptic specialization membrane
plasma membrane	IEA	22301074

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

cell projection [inference]

plasma membrane bounded cell projection [inference]

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
beta-catenin binding
calcium ion binding	IEA	22301074 30032202
cadherin binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Cadherin conserved site
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily

Ortholog

Displaying entries **81 - 90** of 99 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Salmo trutta	115158616		SALTR107815
Salmo trutta	115169648		SALTR40817
Takifugu rubripes	115247939		TAKRU32783
Salarias fasciatus	115405654		SALFA32619
Gadus morhua	115549004		GADMO59206
Sparus aurata	115572229		SPAAU38249
Corvus moneduloides	116451052		CORMO08864
Rhinolophus ferrumequinum	117011719		RHIFE19868
Scophthalmus maximus	118311597		SCOMX29034
Balaenoptera musculus	118880105	9771_0:00339e