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stress-associated endoplasmic reticulum protein 1

Summary

Gene Symbol

Serp1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

28146

PubChem

28146

Alliance of Genome Resources

MGI:92638

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Transmembrane helix
Unfolded protein response

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Z1W5	Ribosome-attached membrane protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
positive regulation of translation	IMP	16415102
skeletal system development	IMP	16415102
glucose metabolic process	IMP	16415102
insulin secretion	IMP	16415102
muscle organ morphogenesis	IMP	16415102

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

multicellular organismal process [inference]

post-embryonic development

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

muscle organ morphogenesis

anatomical structure development [inference]

system development [inference]

skeletal system development

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

establishment of localization [inference]

transport [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

secretion [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

organic substance transport [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

amide transport [inference]

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of amide metabolic process [inference]

positive regulation of translation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth

regulation of developmental growth [inference]

regulation of organ growth [inference]

positive regulation of organ growth

positive regulation of developmental growth [inference]

positive regulation of organ growth

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth

positive regulation of multicellular organismal process [inference]

positive regulation of organ growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of organ growth [inference]

positive regulation of organ growth

positive regulation of developmental growth [inference]

positive regulation of organ growth

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of multicellular organismal process [inference]

regulation of organ growth [inference]

positive regulation of organ growth

positive regulation of multicellular organismal process [inference]

positive regulation of organ growth

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

regulation of growth hormone secretion [inference]

positive regulation of growth hormone secretion

positive regulation of peptide hormone secretion [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA
cytoplasmic microtubule	ISO
endoplasmic reticulum membrane
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

cytoplasmic microtubule

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	181669	WB:WBGene00010337
Caenorhabditis elegans	259582	WB:WBGene00020374
Drosophila melanogaster	251645	FB:FBgn0047135
Callorhinchus milii	103184457		CALMI29950
Danio rerio	336797	ZFIN:ZDB-GENE-030131-8741	DANRE13354
Danio rerio	436846	ZFIN:ZDB-GENE-040718-312	DANRE29042
Astyanax mexicanus	103025790		ASTMX06488
Astyanax mexicanus	103030196		ASTMX09199
Ictalurus punctatus	124627930		ICTPU27976
Electrophorus electricus	113570095		ELEEL09142

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Acknowledgements