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adrenoceptor beta 1

Summary

Gene Symbol

ADRB1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281604
PubChem: 281604

Annotation

Keyword

Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9TT96	Beta-1 adrenoreceptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of heart contraction
positive regulation of MAPK cascade
positive regulation of heart rate by epinephrine-norepinephrine	IEA	30032202
regulation of circadian sleep/wake cycle, sleep
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasodilation [inference]

norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of heart contraction

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

positive regulation of heart contraction

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

positive regulation of blood circulation [inference]

positive regulation of heart contraction

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of heart contraction

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

regulation of biological quality [inference]

regulation of heart rate [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate by epinephrine-norepinephrine

regulation of blood pressure [inference]

negative regulation of blood pressure [inference]

negative regulation of systemic arterial blood pressure [inference]

norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation [inference]

norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
early endosome
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

Displaying 1 entry
GO Term	Evidence Code	PMID
beta1-adrenergic receptor activity	IEA	22301074 30032202

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled amine receptor activity [inference]

adrenergic receptor activity [inference]

beta-adrenergic receptor activity [inference]

beta1-adrenergic receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha-2C adrenergic receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
adenylate cyclase-activating adrenergic receptor signaling pathway
adrenergic receptor activity
adrenergic receptor signaling pathway
alpha2-adrenergic receptor activity
epinephrine binding

Displaying **all 3** entries
InterPro
Adrenoceptor family
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **41 - 50** of 61 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Phascolarctos cinereus	110209527		PHACI08975
Papio anubis	110740390		PAPAN03684
Physeter catodon	112064233	9755_0:003ca6
Electrophorus electricus	113586622		ELEEL38049
Bos indicus x Bos taurus	113884527	30522_0:00475b	BOBOX21301
Monodon monoceros	114909018	40151_0:0036d1
Gadus morhua	115531030		GADMO23116
Strigops habroptila	115607979		STRHB04664
Vicugna pacos	116282527	30538_0:001802
Camelus ferus	116666991	419612_0:002127