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cyclic nucleotide gated channel subunit alpha 1

Summary

Gene Symbol

CNGA1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281700
PubChem: 281700

Annotation

Keyword

3D-structure
Calcium channel
Cell membrane
Coiled coil
Direct protein sequencing
Glycoprotein
Ligand-gated ion channel
Reference proteome
Sodium channel
Transmembrane helix
Vision
cAMP-binding
cGMP-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q00194	Cyclic nucleotide-gated cation channel 1 Cyclic nucleotide-gated channel, photoreceptor Rod photoreceptor cGMP-gated cation channel subunit alpha cGMP-gated cation channel alpha-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
monoatomic cation transport
sodium ion transport
calcium ion transport
visual perception
monoatomic cation transmembrane transport	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

organic substance transport [inference]

calcium ion transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
photoreceptor outer segment
plasma membrane	IEA	30032202
intracellular cyclic nucleotide activated cation channel complex	IEA	30032202
rod photoreceptor outer segment
transmembrane transporter complex

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

transporter complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

cellular anatomical entity [inference]

photoreceptor outer segment

rod photoreceptor outer segment

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
intracellular cAMP-activated cation channel activity	IEA	30032202
intracellular cGMP-activated cation channel activity	IEA	30032202
calcium channel activity
sodium channel activity
cAMP binding

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

ion binding [inference]

anion binding [inference]

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cyclic nucleotide-gated cation channel

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cGMP binding
intracellular cAMP-activated cation channel activity
intracellular cGMP-activated cation channel activity
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 5** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Cyclic nucleotide-binding domain
Cyclic nucleotide-binding, conserved site
Ion transport domain
RmlC-like jelly roll fold

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	1259	HUMAN75472
Mus musculus	12788	MOUSE43501
Rattus norvegicus	85259	RATNO07957
Canis lupus familiaris	403891	CANLF03371
Macaca mulatta	704891	MACMU37472
Pan troglodytes	739850	PANTR34023
Oryctolagus cuniculus	100009524	RABIT08046
Equus caballus	100061553	HORSE30328
Taeniopygia guttata	100218318	TAEGU23238
Pongo abelii	100455135	PONAB27276