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interferon, beta 1, fibroblast

Summary

Gene Symbol

IFNB1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281845
PubChem: 281845

Annotation

Keyword

Antiviral defense
Cytokine
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P01578

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
natural killer cell activation involved in immune response	IEA	30032202
negative regulation of Lewy body formation
positive regulation of peptidyl-serine phosphorylation of STAT protein	IEA	30032202
B cell proliferation	IEA	30032202
defense response to virus

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

neuron cellular homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of inclusion body assembly [inference]

negative regulation of Lewy body formation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of cellular component biogenesis [inference]

regulation of inclusion body assembly [inference]

negative regulation of inclusion body assembly [inference]

negative regulation of Lewy body formation

regulation of Lewy body formation [inference]

negative regulation of Lewy body formation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of inclusion body assembly [inference]

negative regulation of Lewy body formation

regulation of cellular component organization [inference]

negative regulation of cellular component organization [inference]

negative regulation of inclusion body assembly [inference]

negative regulation of Lewy body formation

regulation of inclusion body assembly [inference]

negative regulation of inclusion body assembly [inference]

negative regulation of Lewy body formation

regulation of Lewy body formation [inference]

negative regulation of Lewy body formation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
type I interferon receptor binding	IEA	30032202
cytokine activity	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

type I interferon receptor binding

receptor ligand activity [inference]

cytokine activity

protein-containing complex binding [inference]

type I interferon receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Interferon beta

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cytokine activity
cytokine receptor binding
defense response to virus
response to exogenous dsRNA

Displaying **all 2** entries
InterPro
Four-helical cytokine-like, core
Interferon alpha/beta/delta

Ortholog

Displaying entries **1 - 10** of **121** in total

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Species	Gene ID	OrthoDB
Sus scrofa	445459	9823_0:00011c
Ovis aries	101103376	9940_0:000a9e
Ovis aries	101103623	9940_0:000833
Tursiops truncatus	101325073	9739_0:00197f
Capra hircus	102181595	9925_0:001a4c
Capra hircus	102181867	9925_0:0018f3
Capra hircus	102189208	9925_0:001a45
Bos mutus	102280497	72004_1:0024d6
Bos mutus	102281065	72004_1:0024d0
Bos mutus	102282466	72004_1:0024d1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements