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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glucose-6-phosphate isomerase
Summary
- Gene Symbol
-
- GPI
- Aliases
-
- AMF
- NLK
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytokine
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Glycolysis
- Growth factor
- Hereditary hemolytic anemia
- Hydroxylation
- Isomerase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Secreted
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2U3TZU2 |
|
| B4DE36 |
|
| P06744 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucose homeostasis | ||
| signal transduction | ||
| in utero embryonic development | ||
| glycolytic process | ||
| response to estradiol |
GO Hierarchy
- signal transduction
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
organic cyclic compound metabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| extracellular region | ||
| secretory granule lumen | ||
| membrane | ||
| ficolin-1-rich granule lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| carbohydrate derivative binding | ||
| glucose-6-phosphate isomerase activity | ||
| ubiquitin protein ligase binding | ||
| monosaccharide binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060058 | lymphoma | |
| DOID:0060254 | Robinow syndrome | |
| DOID:0060283 | peeling skin syndrome | |
| DOID:0060284 | paroxysmal nocturnal hemoglobinuria | |
| DOID:0060578 | Noonan syndrome 1 | |
| DOID:0060580 | Noonan syndrome 2 | |
| DOID:0060581 | Noonan syndrome 3 | |
| DOID:0060582 | Noonan syndrome 4 | |
| DOID:0060583 | Noonan syndrome 5 | |
| DOID:0060584 | Noonan syndrome 6 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000952 | Jaundice |
| HP:0001081 | Cholelithiasis |
| HP:0001082 | Cholecystitis |
| HP:0001249 | Intellectual disability |
| HP:0001251 | Ataxia |
| HP:0001324 | Muscle weakness |
| HP:0001744 | Splenomegaly |
| HP:0001930 | Nonspherocytic hemolytic anemia |
| HP:0003568 | Decreased glucosephosphate isomerase level |
| Disease ID | Disease Name |
|---|---|
| OMIM:613470 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100008744 | RABIT10855 | ||
| 105993155 | DIPOR17580 | ||
| 14751 | MGI:95797 | MOUSE56447 | |
| 292804 | RGD:2727 | RATNO16818 | |
| 100719769 | CAVPO17023 | ||
| 101570841 | OCTDE14838 | ||
| 101874026 | MELUD03459 | ||
| 102457553 | PELSI10640 | ||
| 100568208 | ANOCA11704 | ||
| 113876580 | BOBOX12470 |
