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prostaglandin E receptor 3

Summary

Gene Symbol

PTGER3

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 282330
PubChem: 282330

Annotation

Keyword

Alternative splicing
Cell membrane
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P34979	Prostanoid EP3 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
inflammatory response	IEA	30032202
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA	30032202
phospholipase C-activating G protein-coupled receptor signaling pathway	IEA	30032202
positive regulation of cytosolic calcium ion concentration	IEA	30032202
intestine smooth muscle contraction	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

phasic smooth muscle contraction [inference]

intestine smooth muscle contraction

gastro-intestinal system smooth muscle contraction [inference]

intestine smooth muscle contraction

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

negative regulation of biological process [inference]

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
prostaglandin E receptor activity	IEA	22301074 30032202

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled receptor

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	5733	HUMAN50388
Mus musculus	19218	MOUSE37148
Rattus norvegicus	24929	RATNO23869
Sus scrofa	396811	PIGXX30147
Pan troglodytes	456940	PANTR21375
Macaca mulatta	703398	MACMU22511
Danio rerio	100000544	DANRE37622
Oryctolagus cuniculus	100009389	RABIT03797
Equus caballus	100053557	HORSE34978
Pongo abelii	100447375	PONAB19657