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Standards Ontologies Notations
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary
Gene Symbol
  • ST8SIA1
Organism
Bos taurus (domestic cattle)
NCBI Gene
282352
KEGG Gene ID
bta:282352
PubChem
282352
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid biosynthesis
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q6ZXD2
  • Alpha-2,8-sialyltransferase 8A
  • Ganglioside GD3 synthase
  • Ganglioside GT3 synthase
  • Sialyltransferase 8A
  • Sialyltransferase St8Sia I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 4 entries
GO Term Evidence Code PMID
protein glycosylation
oligosaccharide metabolic process
N-glycan processing
sphingolipid metabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K03371
Name
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]
References
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R13175
R06032
R05947
R05940
Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 61 - 70 of 93 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
108279490 ICTPU13124
108541110 RHIBE08570
109045336 CYPCA61960
109066147 CYPCA32481
109316395 CROPO05132
109559591 9915_0:000ee4
112917220 VULVU07298
113584008 ELEEL31963
113892562 30522_0:00108a BOBOX39822
114025344 VOMUR06263
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024