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cadherin 1

Summary

Gene Symbol

CDH1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 282637
PubChem: 282637

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Cytoplasm
Disulfide bond
Endosome
Glycoprotein
Golgi apparatus
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6R8F2	Epithelial cadherin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA	30032202
synapse assembly
adherens junction organization	IEA	30032202
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction organization [inference]

synapse organization [inference]

synapse assembly

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

multicellular organism development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA	22301074
endosome
adherens junction	IEA	30032202
cell-cell junction
catenin complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
beta-catenin binding
calcium ion binding	IEA	22301074 30032202
cadherin binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Cadherin conserved site
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily

Ortholog

Displaying entries **21 - 30** of 76 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ovis aries	101119747	9940_0:00333f	SHEEP05162
Gorilla gorilla gorilla	101145191		GORGO12241
Tursiops truncatus	101329321	9739_0:00418f	TURTR11482
Octodon degus	101586705		OCTDE03523
Jaculus jaculus	101597904		JACJA13186
Mustela putorius furo	101682346		MUSPF16984
Heterocephalus glaber	101719565		HETGA10407
Ictidomys tridecemlineatus	101968091		ICTTR11874
Chinchilla lanigera	102006134		CHILA18749
Macaca fascicularis	102143513		MACFA25218