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hyaluronan synthase 1

Summary

Gene Symbol

Has1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

282821

KEGG Gene ID

rno:282821

PubChem

282821

Alliance of Genome Resources

RGD:708528

Annotation

Keyword

Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8CH93

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
polysaccharide biosynthetic process	ISO
polysaccharide biosynthetic process	IBA
negative regulation of fibroblast migration	ISO
hyaluronan biosynthetic process	ISO
hyaluronan biosynthetic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

reproductive process [inference]

multicellular organismal reproductive process [inference]

ovulation cycle [inference]

estrous cycle

rhythmic process [inference]

ovulation cycle [inference]

estrous cycle

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

response to platelet-derived growth factor [inference]

cellular response to platelet-derived growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to platelet-derived growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to platelet-derived growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

negative regulation of fibroblast migration

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

regulation of cellular process [inference]

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

negative regulation of fibroblast migration

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of fibroblast migration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	ISO
Golgi apparatus	ISO
plasma membrane	ISO
plasma membrane	IBA
membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
identical protein binding	ISO
hyaluronan synthase activity	ISO
hyaluronan synthase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

hyaluronan synthase activity

hexosyltransferase activity [inference]

hyaluronan synthase activity

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00752

Name

hyaluronan synthase [EC:2.4.1.212]

References

8366070

Rhea

RHEA:12528

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.212

PMID

RHEA:20465

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.212

PMID

Ortholog

Displaying entries **71 - 73** of 73 in total

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Species	Gene ID	Orthologous MAtrix
Scophthalmus maximus	118300444	SCOMX16463
Panthera leo	122208867	PANLE28963
Ursus americanus	123778043	URSAM27169

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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External Links

Annotation

KEGG BRITE Database

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Acknowledgements