GlyCosmos Portal

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Inflammatory response
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8HZR3	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Fucosyltransferase 4 Fucosyltransferase IV Galactoside 3-L-fucosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein glycosylation	IEA	22301074 30032202
protein N-linked glycosylation
protein O-linked glycosylation
glycosphingolipid biosynthetic process
inflammatory response

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

Lewis x epitope biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

Lewis x epitope biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

Lewis x epitope biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
trans-Golgi network
membrane	IEA	22301074 30032202
Golgi cisterna membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity
alpha-(1->3)-fucosyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

alpha-(1->3)-fucosyltransferase activity

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Fucosyltransferase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-(1->3)-fucosyltransferase activity
fucosylation
fucosyltransferase activity
transferase activity

Displaying **all 3** entries
InterPro
Fucosyltransferase, N-terminal
GT10-like, C-terminal domain superfamily
Glycosyl transferase family 10

KEGG BRITE Database

Orthology

K07632

Name

galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-]

References

Reactions

Displaying entries **1 - 10** of 11 in total

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KEGG Reaction	Enzyme	Acceptor	Product
R06221	2.4.1.- 2.4.1.152 2.4.1.65	G76439VL	G91560NT
R06224	2.4.1.- 2.4.1.152 2.4.1.65	G52160KJ	G20180GO
R06230	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G65223RT
R06038	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G76439VL
R06075	2.4.1.- 2.4.1.65	G01767JJ	G96401FK
R06076	2.4.1.- 2.4.1.152 2.4.1.65	G66427ZQ	G07075ZE
R06039	2.4.1.- 2.4.1.152 2.4.1.65	G77285LE	G00851XQ
R06227	2.4.1.- 2.4.1.152 2.4.1.65	G07075ZE	G03564IA
R06222	2.4.1.- 2.4.1.152 2.4.1.65	G00851XQ	G52160KJ
R06095	2.4.1.- 2.4.1.152 2.4.1.65	G13636IT	G89659QV

Rhea

RHEA:14257

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

a β-D-galactosyl-(1→4)-[α-L-fucosyl-(1→3)]-N-acetyl-β-D-glucosaminyl derivative + H⁺ + GDP

Enzyme

2.4.1.152

PMID

Ortholog

Displaying entries **1 - 10** of 20 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	2526	HUMAN08853
Mus musculus	14345	MOUSE61918
Rattus norvegicus	60670	RATNO42266
Pan troglodytes	449507	PANTR04110
Monodelphis domestica	100013730	MONDO21043
Callithrix jacchus	100410367	CALJA05171
Pongo abelii	100448470	PONAB04196
Pan paniscus	100982519	PANPA07757
Papio anubis	101010665	PAPAN06002
Chinchilla lanigera	102025531	CHILA25128

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements