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succinate dehydrogenase complex iron sulfur subunit B

Summary

Gene Symbol

SDHB

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 286840
KEGG Gene ID: bta:286840
PubChem: 286840

Annotation

Keyword

2Fe-2S
3Fe-4S
4Fe-4S
Acetylation
Electron transport
Mitochondrion inner membrane
Oxidoreductase
Reference proteome
Transit peptide
Tricarboxylic acid cycle

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A452DI87
Q3T189	Iron-sulfur subunit of complex II Malate dehydrogenase [quinone] iron-sulfur subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
aerobic respiration	IEA	30032202
respiratory electron transport chain	IEA	30032202
tricarboxylic acid cycle	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

electron transport chain [inference]

respiratory electron transport chain

primary metabolic process [inference]

tricarboxylic acid cycle

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

electron transport chain [inference]

respiratory electron transport chain

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrial membrane	IEA	30032202
mitochondrial inner membrane
respiratory chain complex II

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

respiratory chain complex [inference]

respiratory chain complex II

catalytic complex [inference]

respiratory chain complex II

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
2 iron, 2 sulfur cluster binding	IEA	22301074
succinate dehydrogenase (ubiquinone) activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity

oxidoreductase activity, acting on the CH-CH group of donors [inference]

succinate dehydrogenase activity [inference]

succinate dehydrogenase (ubiquinone) activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

quinone binding [inference]

ubiquinone binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

succinate dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
2 iron, 2 sulfur cluster binding
3 iron, 4 sulfur cluster binding
4 iron, 4 sulfur cluster binding
aerobic respiration
iron-sulfur cluster binding
metal ion binding
oxidoreductase activity
respiratory electron transport chain
tricarboxylic acid cycle

Displaying **all 9** entries
InterPro
2Fe-2S ferredoxin, iron-sulphur binding site
2Fe-2S ferredoxin-like superfamily
2Fe-2S ferredoxin-type iron-sulfur binding domain
4Fe-4S ferredoxin, iron-sulphur binding, conserved site
4Fe-4S ferredoxin-type, iron-sulphur binding domain
Alpha-helical ferredoxin
Beta-grasp domain superfamily
Succinate dehydogenase/fumarate reductase N-terminal
Succinate dehydrogenase/fumarate reductase iron-sulphur protein

KEGG BRITE Database

Orthology

K00235

Name

succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]

References

2302193

Rhea

succinate

fumarate

Enzyme

1.3.5.1

PMID

a quinone + succinate

a quinol + fumarate

Enzyme

1.3.5.1

PMID

succinate

fumarate

Enzyme

1.3.5.1

PMID

succinate

fumarate

Enzyme

1.3.5.1

PMID

Ortholog

Displaying entries **41 - 50** of **109** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Bos mutus	102274978	72004_1:003cde
Haplochromis burtoni	102293590			HAPBU15940
Latimeria chalumnae	102358325			LATCH13447
Bubalus bubalis	102407691	89462_0:0005f8
Camelus ferus	102524547	419612_0:0028f5
Vicugna pacos	102541082	30538_0:001aa3
Poecilia formosa	103150475			POEFO16149
Callorhinchus milii	103187447			CALMI36772
Chlorocebus sabaeus	103220068			CHLSB09325
Chlorocebus sabaeus	103225507			CHLSB09325

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024