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phosphoglycolate phosphatase

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

287115

PubChem

287115

Alliance of Genome Resources

RGD:1307773

Annotation

Keyword

Carbohydrate metabolism
Magnesium
Metal-binding
Protein phosphatase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
D3ZDK7	Aspartate-based ubiquitous Mg(2+)-dependent phosphatase Phosphoglycolate phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycerol biosynthetic process	IDA IEA ISO	26755581
negative regulation of gluconeogenesis	IEA IMP ISO	26755581
glycerophospholipid metabolic process	IEA IMP ISO	26755581

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	TAS
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	ISO
phosphoglycolate phosphatase activity	IEA ISO
glycerol-3-phosphatase activity	IBA IEA IMP ISO	26755581
magnesium ion binding	ISO
ADP phosphatase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

glycerol-1-phosphatase activity

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

nucleoside diphosphate phosphatase activity [inference]

ADP phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

phosphoglycolate phosphatase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism

Displaying **all 3** entries
Gene Ontology
glycerol-3-phosphatase activity
hydrolase activity
metal ion binding

Displaying **all 4** entries
InterPro
2-phosphoglycolate phosphatase, eukaryotic
HAD superfamily
HAD-like superfamily
HAD-superfamily hydrolase, subfamily IIA

Rhea

RHEA:10684

H₂O

phosphate

Enzyme

3.1.3.48

PMID

RHEA:66372

H₂O + sn-glycerol 3-phosphate

glycerol + phosphate

Enzyme

3.1.3.21

RHEA:46084

H₂O + sn-glycerol 1-phosphate

glycerol + phosphate

Enzyme

3.1.3.21

PMID

Ortholog

Displaying entries **1 - 10** of 54 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	37541		FB:FBgn0034713
Drosophila melanogaster	38358		FB:FBgn0052487
Drosophila melanogaster	39985		FB:FBgn0036759
Drosophila melanogaster	39986		FB:FBgn0036760
Mus musculus	67078	10090_1:004d27	MGI:1914328
Caenorhabditis elegans	178963		WB:WBGene00019604
Caenorhabditis elegans	178964		WB:WBGene00016892
Caenorhabditis elegans	178965		WB:WBGene00018424
Caenorhabditis elegans	183469		WB:WBGene00016664
Homo sapiens	283871		HGNC:8909