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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione peroxidase 3
Summary
- Gene Symbol
-
- GPX3
- Aliases
-
- selenoprotein GPX3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Peroxidase
- Reference proteome
- Secreted
- Selenocysteine
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P22352 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide catabolic process | ||
| cellular oxidant detoxification | ||
| response to lipid hydroperoxide |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| selenium binding | ||
| identical protein binding | ||
| glutathione peroxidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glutathione peroxidase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- V: Defense mechanisms
| Gene Ontology |
|---|
| cellular oxidant detoxification |
| oxidoreductase activity |
| response to oxidative stress |
| InterPro |
|---|
| Glutathione peroxidase conserved site |
| Glutathione peroxidase |
| Thioredoxin-like superfamily |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050731 | vitamin B12 deficiency | |
| DOID:0050860 | colorectal adenoma | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080797 | nasal type extranodal NK/T-cell lymphoma | |
| DOID:10534 | stomach cancer | |
| DOID:10590 | mild pre-eclampsia | |
| DOID:10591 | pre-eclampsia | |
| DOID:10763 | hypertension | |
| DOID:11446 | sciatic neuropathy |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001191
- Gene Name
- glutathione peroxidase 3 (plasma)
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14778 | MGI:105102 | MOUSE05707 | ||
| 29327 | RGD:69224 | |||
| 181178 | WB:WBGene00007516 | |||
| 182513 | WB:WBGene00007517 | |||
| 190801 | WB:WBGene00022377 | |||
| 281210 | BOVIN33771 | |||
| 394558 | Xenbase:XB-GENE-5884491 | |||
| 443744 | Xenbase:XB-GENE-5884731 | |||
| 444571 | Xenbase:XB-GENE-6254881 | |||
| 471703 | 9598_0:001abc |
