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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione peroxidase 3
Summary
- Gene Symbol
-
- GPX3
- Aliases
-
- selenoprotein GPX3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Peroxidase
- Reference proteome
- Secreted
- Selenocysteine
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P22352 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide catabolic process | ||
| cellular oxidant detoxification | ||
| response to lipid hydroperoxide |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| selenium binding | ||
| identical protein binding | ||
| glutathione peroxidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glutathione peroxidase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- V: Defense mechanisms
| Gene Ontology |
|---|
| cellular oxidant detoxification |
| oxidoreductase activity |
| response to oxidative stress |
| InterPro |
|---|
| Glutathione peroxidase conserved site |
| Glutathione peroxidase |
| Thioredoxin-like superfamily |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4914 | esophagus adenocarcinoma | |
| DOID:4948 | gallbladder carcinoma | |
| DOID:5041 | esophageal cancer | |
| DOID:6713 | cerebrovascular disease | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:7941 | Barrett's adenocarcinoma | |
| DOID:850 | lung disease | |
| DOID:9206 | Barrett's esophagus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9408 | acute myocardial infarction |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001191
- Gene Name
- glutathione peroxidase 3 (plasma)
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 713057 | MACMU38162 | |||
| 798788 | ZFIN:ZDB-GENE-070222-3 | DANRE07881 | ||
| 100171486 | 9601_0:00169b | PONAB29710 | ||
| 100395166 | CALJA26334 | |||
| 100473120 | AILME11242 | |||
| 100580839 | NOMLE24758 | |||
| 100674572 | LOXAF20182 | |||
| 100732539 | CAVPO20580 | |||
| 100764638 | CRIGR06021 | |||
| 100995142 | 9597_0:001912 |
