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drosha ribonuclease III

Summary

Gene Symbol

DROSHA

Organism

Homo sapiens (human)

External Links

NCBI Gene

29102

PubChem

29102

Alliance of Genome Resources

HGNC:17904

JoGo

DROSHA

TogoVar

DROSHA

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Endonuclease
Magnesium
Manganese
Metal-binding
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repeat
Ribosome biogenesis

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NRR4	Protein Drosha Ribonuclease III p241

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
rRNA processing	IEA
miRNA metabolic process	IEA
positive regulation of gene expression	IEA
primary miRNA processing	IDA	14508493 15574589
primary miRNA processing	IMP	14508493

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

regulatory ncRNA processing [inference]

miRNA processing [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of miRNA metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of miRNA metabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of RNA metabolic process [inference]

regulation of miRNA metabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of miRNA metabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of miRNA metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
postsynaptic density	IEA
microprocessor complex	IDA	15574589
microprocessor complex	IBA
microprocessor complex	IPI	24581491
glutamatergic synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

microprocessor complex

intracellular protein-containing complex [inference]

endonuclease complex [inference]

endoribonuclease complex [inference]

ribonuclease III complex [inference]

microprocessor complex

catalytic complex [inference]

endonuclease complex [inference]

endoribonuclease complex [inference]

ribonuclease III complex [inference]

microprocessor complex

cellular anatomical entity [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

postsynaptic specialization [inference]

postsynaptic density

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	IDA	20180804
RNA binding	IPI	31507089
RNA binding	HDA	22658674 22681889
ribonuclease III activity	IDA	14508493 15574589
ribonuclease III activity	IBA