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synapsin II

Summary

Gene Symbol

Syn2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29179

PubChem

29179

Alliance of Genome Resources

RGD:3798

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6IKX9	Synapsin II
Q63537	Synapsin II
A6IKY0	Synapsin II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
neurotransmitter secretion	ISS
neurotransmitter secretion	ISO
neurotransmitter secretion	IEA
calcium-ion regulated exocytosis	ISO
calcium-ion regulated exocytosis	IEA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle cycle

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle cycle

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of localization in cell [inference]

organelle localization [inference]

vesicle localization [inference]

synaptic vesicle localization [inference]

synaptic vesicle clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IEA
synaptic vesicle	TAS	2506642
synaptic vesicle	IDA	11867766
postsynaptic density	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

SNARE complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

extrinsic component of membrane [inference]

extrinsic component of organelle membrane [inference]

extrinsic component of synaptic vesicle membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

postsynaptic specialization [inference]

postsynaptic density

presynapse

terminal bouton

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	11867766 17442889
ATP binding	IEA
cytoskeletal protein binding	TAS	2506642
identical protein binding	ISO
identical protein binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Synapsin

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 5** entries
InterPro
ATP-grasp fold, subdomain 1
Pre-ATP-grasp domain superfamily
Synapsin, ATP-binding domain
Synapsin, pre-ATP-grasp domain
Synapsin

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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