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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
troponin I3, cardiac type
Summary
- Gene Symbol
-
- Tnni3
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Actin-binding
- Muscle protein
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P23693 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| striated muscle contraction | ||
| regulation of cardiac muscle contraction by calcium ion signaling | ||
| cardiac muscle contraction | ||
| heart development | ||
| regulation of smooth muscle contraction |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin binding | ||
| actin filament binding | ||
| calcium channel inhibitor activity | ||
| calcium-dependent protein binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Troponin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| actin binding |
| cardiac muscle contraction |
| skeletal muscle contraction |
| InterPro |
|---|
| Troponin I residues 1-32 |
| Troponin domain superfamily |
| Troponin |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0110313 | hypertrophic cardiomyopathy 7 | |
| DOID:0110459 | dilated cardiomyopathy 1FF | |
| DOID:0110460 | dilated cardiomyopathy 2A | |
| DOID:0111425 | restrictive cardiomyopathy 1 | |
| DOID:114 | heart disease | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:299 | adenocarcinoma | |
| DOID:3393 | coronary artery disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 7137 | HGNC:11947 | HUMAN46130 | ||
| 21954 | 10090_1:002747 | MGI:98783 | MOUSE54212 | |
| 32794 | FB:FBgn0283471 | |||
| 177295 | WB:WBGene00006586 | |||
| 180127 | WB:WBGene00006585 | |||
| 402809 | ZFIN:ZDB-GENE-040718-80 | |||
| 403566 | CANLF00647 | |||
| 445029 | ZFIN:ZDB-GENE-040801-9 | |||
| 492493 | ZFIN:ZDB-GENE-041114-60 | |||
| 494164 | ZFIN:ZDB-GENE-040625-119 |
