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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

kallikrein 1-related peptidase C10

Summary

Gene Symbol

Klk1c10

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

292858

PubChem

292858

Alliance of Genome Resources

RGD:1561403

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Reference proteome
Serine protease
Signal
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
P36375	Endopeptidase K Proteinase B T-kininogenase Tissue kallikrein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of antibacterial peptide production	ISO
regulation of systemic arterial blood pressure
proteolysis	ISO
zymogen activation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

primary metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

regulation of defense response to bacterium [inference]

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

regulation of response to external stimulus [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

regulation of defense response to bacterium [inference]

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

regulation of defense response to bacterium [inference]

positive regulation of defense response to bacterium [inference]

positive regulation of antibacterial peptide production

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antimicrobial peptide production [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of antibacterial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of antimicrobial peptide production [inference]

positive regulation of antibacterial peptide production

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	ISO
secretory granule
protein-containing complex	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endopeptidase activity	ISO
serine-type endopeptidase activity	ISO
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isoform A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
proteolysis
serine-type endopeptidase activity

Displaying **all 6** entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026