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serpin family H member 1

Summary

Gene Symbol

Serpinh1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29345

PubChem

29345

Alliance of Genome Resources

RGD:69302

Annotation

Keyword

Acetylation
Chaperone
Direct protein sequencing
Endoplasmic reticulum
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Stress response

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P29457	47 kDa heat shock protein Collagen-binding protein GP46
A6I6G9	Collagen-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
chondrocyte development involved in endochondral bone morphogenesis	ISO
chondrocyte development involved in endochondral bone morphogenesis	IEA
response to organic cyclic compound
collagen fibril organization	ISO
collagen fibril organization	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

biosynthetic process [inference]

collagen biosynthetic process

collagen metabolic process [inference]

collagen biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

protein maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

chondrocyte development [inference]

chondrocyte development involved in endochondral bone morphogenesis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

supramolecular fiber organization [inference]

collagen fibril organization

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

chondrocyte development [inference]

chondrocyte development involved in endochondral bone morphogenesis

cellular developmental process [inference]

cell development [inference]

chondrocyte development [inference]

chondrocyte development involved in endochondral bone morphogenesis

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin D

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin D

response to organic substance [inference]

response to organic cyclic compound

response to vitamin D

response to lipid [inference]

response to vitamin D

response to oxygen-containing compound [inference]

response to vitamin D

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular space	IEA
cytoplasm	ISO
endoplasmic reticulum	ISO
endoplasmic reticulum	IBA
endoplasmic reticulum	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

membrane microdomain [inference]

membrane raft

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
serine-type endopeptidase inhibitor activity	IBA
serine-type endopeptidase inhibitor activity	IEA
collagen binding	TAS	1654327
collagen binding	IEA
unfolded protein binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

unfolded protein binding

protein-containing complex binding [inference]

collagen binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1,

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
collagen binding
collagen fibril organization
serine-type endopeptidase inhibitor activity

Displaying **all 7** entries
InterPro
Serpin H1, serpin domain
Serpin domain
Serpin family
Serpin superfamily, domain 1
Serpin superfamily, domain 2
Serpin superfamily
Serpin, conserved site

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	183	FB:FBgn0037772
Homo sapiens	871	Xenbase:XB-GENE-1005105	HUMAN08278
Mus musculus	12406	Xenbase:XB-GENE-1005105	MOUSE54981
Drosophila melanogaster	24179	FB:FBgn0037772
Xenopus tropicalis	29345	Xenbase:XB-GENE-1005105
Danio rerio	30449		DANRE08302
Danio rerio	40234	ZFIN:ZDB-GENE-080219-21
Drosophila melanogaster	284293	FB:FBgn0037772
Sus scrofa	396773		PIGXX35012
Pan troglodytes	466899		PANTR03863